Triterpene sapogenins with oleanene skeleton: chemotypes and biological activities.

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Triterpene sapogenins with oleanene skeleton: chemotypes and biological activities.

Critical survey of a selected class of pentacyclic triterpenes--the oleanane family, is presented based on current literature in order to underline their value for medicinal chemistry and drug development potential. Oleanenes may be considered as a renewable resource of valuable research materials which are structurally diverse, inherently biocompatible and have built-in affinity for many categ...

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Saponins, an important group of bioactive plant natural products, are glycosides of triterpenoid or steroidal aglycones (sapogenins). Saponins possess many biological activities, including conferring potential health benefits for humans. However, most of the steps specific for the biosynthesis of triterpene saponins remain uncharacterized at the molecular level. Here, we use comprehensive gene ...

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ژورنال

عنوان ژورنال: Acta Biochimica Polonica

سال: 2014

ISSN: 1734-154X,0001-527X

DOI: 10.18388/abp.2014_1890